Buprenorphine

A cardioprotective analgesic for acute MI?

Client:
Reckitt & Colman
Category:
Pain

Cutting-edge science and differentiation

Previously-unknown relationships are revealed by McCormack’s initial CEME probe. This is then followed with a new analysis by McCormack which suggests the novel prospect of cardioprotective effects of buprenorphine in patients with acute MI.

Clinical implications of new teachings

These new findings suggest that buprenorphine may be the opioid of choice in managing the pain of MI.

A young female doctor lies on the bed beside her female patient
© Shutterstock

Key outcomes

  • Expansion of use within an approved indication
  • Prospect of a new indication as a cardioprotective agent
  • Prospect of new IP within a new indication

Published new teachings

  • McCormack K, Chapleo C. ‘Opioid Receptors and Myocardial Protection: Do some opioid agonists possess cardioprotective effects?’. Clinical Drug Investigation, 1998 15(5) 445-454.